Jakarta, June 10th, 2023. Various tissue engineering researches and innovations in the field of medicine have developed rapidly and produced many biological products that can speed up the wound healing process. This development will greatly impact the results of operations, especially in the field of Facial Plastic and Reconstructive Surgery of Ear Nose Throat Head Neck. This was conveyed by Prof. Dr. dr. Mirta Hediyati Reksodiputro, Sp.T.H.T.B.K.L., Subsp.F.P.R.(K)., when delivering her professorial inaugural speech this morning (Saturday, 10/6), in the IMERI Hall, UI Campus, Salemba, Jakarta. According to her, one of the biological products currently widely used in the wound healing process is Platelet Rich Plasma (PRP).
However, Prof. Mirta mentioned that PRP has several drawbacks, including that PRP is in the form of a liquid and the manufacturing process requires bovine thrombin, which is xenologous (different species) in nature. Currently, another form of autologous platelet preparation has been developed, namely Platelet Rich Fibrin Matrix (PRFM), which has a denser and more flexible structure.
PRFM is the latest generation of platelet concentrate that produces natural fibrin in which the platelets are dispersed in it. PRFM also acts as a scaffold that will help localize growth factors.
Many operations and procedures in the field of ENT Facial Plastic and Reconstructive Surgery use a lot of platelet concentrate products, such as PRP platelet gel, Platelet Rich Fibrin (PRF), and PRFM. In polyclinic services, platelet products are often used for wound care. These platelet products contain growth factors, adhesive factors, chemokines, cytokines, angiogenesis, and other substances that play a role in tissue engineering. Prof. Mirta said that all of these ingredients are very important for tissue engineering, which is why platelet concentrate products are widely used in various fields of medicine.
Based on various studies that have been conducted, it is known that autologous platelet concentrates as a source of growth factors have many benefits in tissue engineering, both for facial plastic reconstruction and other sciences. Currently, the application method of autologous platelet concentrate products continues to develop in various health services in order to improve the quality of human life.
“There are still many potential benefits of autologous platelet concentrates that can be developed and used for various health treatments. It is a dream for all of us to produce new innovations for the purpose of making the nation healthy. We can continue to work by producing new innovations regarding this autologous platelet concentrate,” said Prof. Mirta.
Through her research entitled “The Latest Application of Autologous Platelet Concentrates in Tissue Engineering to Improve the Quality of Human Life”, Prof. Mirta succeeded in becoming a Professor in the Field of Plastic Facial Reconstruction of Ear Nose Throat Head and Neck Surgery at FKUI.
Prof. Mirta successfully completed the General Practitioner Education Program at FKUI in 1999. Still at the same campus, Prof. Mirta won the BKL ENT Specialist-1 title in 2006. Then, she continued her Fellowship in Rhinoplasty, Otorhinolaryngology Department, Asan Medical Center, Seoul, South Korea. In 2014, she managed to get the cum laude predicate in the FKUI Doctoral Program in Medical Sciences.
Some of her scientific works in recent years, includes Single stage maxillofacial reconstruction combined radical surgery for managing juvenile ossifying fibroma: A Case Report (2023); Stability Evaluation of Royal Jelly Gel (2023); The Effect of Plastic Tape Seal to Reduce Face Seal Leak in Respirator N-95 type 1860 (2023); Multiple Approaches for Managing Complex Ophthalmic Blunt Trauma: A Case Report (2021); and Efficacy of Combining Hyaluronic Acid and Platelet-Rich Fibrin in Diabetic Foot Ulcer (2021).